Annie Knowby found herself in Hell surrounded by Demons and Spirits, and figured if she wanted to return to the land of the living, she would need help fighting her way through, so using the pages of the Necronomicon Ex-Mortis, Ash's severed hand and a shedding of her own blood, she created a new Ash Williams, except he doesn't remember anything after cutting off his hand. After sometime of looking for a way out of Hell, Annie and Ash find out that they can open a portal back to the living world, but before they begin to work on the portal, Ash is possessed by a demon and attacks Annie. She stabs him with the Kandarian Dagger, and he returns to normal and sets out to find Annie's parents, whose souls are trapped inside the ruler of Hell, Rabisu. He defeats Rabisu and frees the Knowby family once him and Annie return to the land of the living.
Some time has passed since he and Annie escaped Hell, and now Ash finds himself living in a trailer in Texas. One day while sitting on the toilet reading a newspaper, the trailer is teleported into Hell and Ash finds that a demon named Hastur wants him to kill the newly resurrected Adolf Hitler, and in return, Hastur will remove the evil spirit from Ash so he can never become a Deadite again. Ash thinks that's a pretty good deal until he finds that Hitler is indestructible thanks to tattoos of passages from the Necronomicon. After Adolf thinks he is about to defeat Ash, Ash kicks him in the nuts and realizes that not every part of Hitler is tattooed, so Ash shoots Hitler in the head, killing him once and for all. Hastur tells Ash that being in Ash's debt is a sign of weakness, so Ash shoots two out of the three heads Hastur has, and the remaining head tells Ash that it needed the combined power of all three to remove the evil, so Ash just has what's left of Hastur send him home.
While hunting down the evil forces that he and Annie Knowby unleashed, the simulacrum Ash had his copy of the Necronomicon stolen from him by a woman in a bar. Ash tracked the woman to Romania, just in time to watch her successfully resurrect Dracula. Ash's battle with Dracula was interrupted by a demon named Hzxyrioth, who had been looking for the Book of The Dead. Dracula and Ash teamed-up to defeat Hzxyrioth, and used the Ex-Mortis to send him somewhere in time and space. Just as Dracula was going to kill Ash, he was stabbed in the heart with a wooden stake by the simulacrum, turning him to dust instantly. Ash grabbed the book and headed back to America.
Sometime after returning to the stateside, Ash became an Uber driver to help pay for repairs for his Oldsmobile. One of his Uber passengers was a US Government agent named Norma, who was heading to the secret government facility Area 54, spotted a Martian Tripod attacking cars on the highway ahead of them. She told Ash that the War of The Worlds was a real event, and that somehow the Martians had come back to life. Arriving at Area 54, Ash and Norma come up with a plan to use dead germs pulled from the corpses of the Martians to destroy the Deadite Martians, since the common cold is what killed them the first time. Ash volunteers to be captured, carrying a sample of the dead germs with him. The germs go airborne, and the Martians are defeated.
Six months since his return from Hell with Annie Knowby, Ash says that over the past six months he is beginning to have feelings for Annie while they round-up the Deadites they unleashed when they returned to the land of the living. He also expresses concern about the real Ash Williams who was sucked back with the evil somewhere in time unknown by both him and Annie. When Annie opens a portal to the Mirror Dimension to send the Deadites back to where they came from, Ash was pulled in because he was created from the original Ash's evil hand, which contained Deadite blood. Both him and Annie are sucked into the Mirror Dimension.
Physically and mentally, Ash is, to all intents and purposes, exactly the same as the original Ash immediately before he cut his hand off. He has no memory of the events between this and the moment Annie created him. Since he is also partially composed of Annie's blood as well, he also possesses some of Annie's attributes, including some of her hormonal responses, much to his alarm. When he was "created", he was initially confused as to his situation, and was disappointed to learn that he wasn't the real Ash. He used this to his advantage, however; since he technically isn't alive, and the real Ash has his soul, the Demons will ignore him. He was, however, briefly susceptible to the Deadite influence because of his infected hand.